Description
Predef 2X Injection 100ml – Professional Veterinary Corticosteroid Solution
Predef 2X Injection 100ml is the gold standard veterinary corticosteroid trusted by livestock veterinarians, equine practitioners, and farm managers worldwide. This powerful anti-inflammatory injection contains isoflupredone acetate 2mg/ml, delivering rapid, reliable relief for inflammatory conditions, allergic reactions, and adrenal insufficiency in horses, cattle, and swine.
For over 30 years, veterinary professionals have relied on Predef 2X as their first-choice treatment for acute inflammatory conditions, emergency allergic reactions, and metabolic disorders across multiple livestock species. Its proven efficacy and safety profile make it an essential component of any comprehensive veterinary treatment protocol.
What Makes Predef 2X the Preferred Choice?
Advanced Corticosteroid Formulation
Isoflupredone acetate, the active ingredient in Predef 2X, is a synthetic corticosteroid with potent anti-inflammatory, anti-allergic, and glucocorticoid activity. Unlike older corticosteroids, isoflupredone provides:
- 4x more potent anti-inflammatory action than prednisolone
- Rapid onset of action within 30-60 minutes
- Extended duration of effect lasting 12-24 hours
- Minimal sodium retention compared to other corticosteroids
- Enhanced tissue penetration for localized treatment
Multi-Species Veterinary Solution
Our 100ml multi-dose vial provides cost-effective treatment across your entire operation, whether you’re managing a single performance horse, a dairy herd, or a commercial swine facility. The sterile formulation maintains potency and safety throughout the recommended usage period.
Comprehensive Treatment Applications
Equine Applications
Predef 2X for horses is extensively used by equine veterinarians for:
Musculoskeletal Conditions:
- Joint inflammation and synovitis
- Tendon and ligament injuries with inflammatory components
- Muscle strains and inflammatory myopathy
- Laminitis management (acute phases)
- Back pain and spinal inflammation
Respiratory Conditions:
- Allergic respiratory disease and heaves
- Inflammatory airway disease (IAD)
- Acute bronchospasm and respiratory distress
- Exercise-induced pulmonary hemorrhage support
Dermatological Conditions:
- Allergic dermatitis and urticaria
- Contact hypersensitivity reactions
- Insect bite hypersensitivity
- Chronic skin inflammation
Systemic Conditions:
- Anaphylactic shock emergency treatment
- Adrenal insufficiency support
- Inflammatory bowel conditions
- Autoimmune disorders
Bovine Applications
Predef 2X for cattle is the veterinarian’s choice for:
Metabolic Disorders:
- Ketosis treatment – improves glucose metabolism and reduces ketone production
- Milk fever adjunct therapy
- Fatty liver syndrome management
- Pregnancy toxemia in beef cattle
Reproductive Health:
- Retained placenta treatment – reduces inflammation and promotes expulsion
- Metritis and endometritis management
- Ovarian cysts and reproductive disorders
- Dystocia recovery support
Mastitis and Udder Health:
- Acute mastitis with severe inflammation
- Chronic mastitis flare-ups
- Udder edema reduction
- Teat injuries and inflammation
Respiratory and Systemic:
- Shipping fever complex
- Pneumonia with inflammatory components
- Allergic reactions to feed or medications
- Heat stress complications
Swine Applications
Predef 2X for pigs effectively treats:
Respiratory Conditions:
- Porcine respiratory disease complex (PRDC)
- Mycoplasma pneumonia inflammatory response
- Acute respiratory distress
- Allergic respiratory reactions
Reproductive Disorders:
- Mastitis-metritis-agalactia (MMA) syndrome
- Farrowing complications and inflammation
- Reproductive tract infections
Stress and Metabolic:
- Transport stress syndrome
- Weaning stress complications
- Feed transition disorders
- Heat stress management
Skin and Systemic:
- Allergic skin reactions
- Contact dermatitis
- Systemic inflammatory responses
Professional Dosage and Administration Guidelines
Equine Dosing Protocol
Standard Dosage: 5-20 mL intramuscularly or intravenously
Condition-Specific Dosing:
- Mild inflammation: 5-10 mL IM once daily
- Moderate conditions: 10-15 mL IM every 12-24 hours
- Severe inflammation/emergency: 15-20 mL IV, may repeat in 6-12 hours
- Maintenance therapy: 5-10 mL every 2-3 days as needed
Weight-Based Dosing:
- 400kg horse: 8-16 mL per dose
- 500kg horse: 10-20 mL per dose
- 600kg horse: 12-24 mL per dose
Bovine Dosing Protocol
Standard Dosage: 5-10 mL intramuscularly or intravenously
Condition-Specific Applications:
- Ketosis: 10 mL IM daily for 3-5 days
- Retained placenta: 10 mL IM, repeat in 12-24 hours if needed
- Acute mastitis: 5-10 mL IM every 12 hours for 2-3 treatments
- Respiratory conditions: 5-10 mL IM daily for 3-5 days
Swine Dosing Protocol
Standard Dosage: 2-5 mL intramuscularly
Weight-Based Recommendations:
- Piglets (10-30kg): 1-2 mL IM
- Growing pigs (30-60kg): 2-3 mL IM
- Finishing pigs (60-100kg): 3-4 mL IM
- Breeding stock (100kg+): 4-5 mL IM
Product Specifications and Quality Assurance
Technical Specifications
- Active Ingredient: Isoflupredone acetate USP
- Concentration: 2.0 mg/mL
- Volume: 100mL sterile multi-dose vial
- pH: 7.0-8.5 (isotonic formulation)
- Preservative: Benzyl alcohol 1% (maintains sterility)
- Storage: Store at 20-25°C (68-77°F), protect from light
- Shelf Life: 24 months unopened, 28 days after first puncture
Manufacturing Excellence
- FDA-approved facility with current Good Manufacturing Practices (cGMP)
- USP pharmaceutical grade raw materials
- Sterile filtration through 0.22-micron filters
- Endotoxin testing ensures pyrogenic safety
- Batch testing for potency, sterility, and safety
- Quality control at every manufacturing step
Professional Packaging
- Type I glass vial with butyl rubber stopper
- Tamper-evident aluminum flip-off cap
- Clear labeling with lot numbers and expiration dates
- Professional packaging suitable for veterinary clinics
- Proper documentation for inventory management
Safety Information and Precautions
Important Safety Considerations
Predef 2X is a potent corticosteroid requiring professional veterinary oversight. Proper usage ensures maximum benefit while minimizing potential adverse effects.
Contraindications:
- Viral infections (may suppress immune response)
- Systemic fungal infections
- Pregnancy (first trimester in cattle and swine)
- Concurrent live virus vaccines
- Known hypersensitivity to corticosteroids
Drug Interactions:
- NSAIDs: Increased risk of gastrointestinal ulceration
- Insulin: May require dosage adjustment in diabetic animals
- Diuretics: Monitor electrolyte balance
- Anticoagulants: Enhanced anticoagulant effects possible
Monitoring Requirements:
- Blood glucose levels in diabetic or susceptible animals
- Electrolyte balance during extended therapy
- Body condition and appetite changes
- Wound healing progress if applicable
Withdrawal Periods (Food-Producing Animals)
Cattle:
- Meat: 4 days after last injection
- Milk: 48 hours after last injection
- Extended therapy: May require longer withdrawal
Swine:
- Meat: 5 days after last injection
- Breeding animals: No withdrawal required
Note: Always follow current FDA withdrawal guidelines and consult veterinary guidance for specific situations.
Potential Adverse Effects
While generally well-tolerated, monitor for:
Short-term Effects:
- Increased appetite and water consumption
- Mild lethargy or behavioral changes
- Injection site sensitivity (rare)
- Temporary immunosuppression
Extended Use Considerations:
- Delayed wound healing
- Increased susceptibility to infections
- Electrolyte imbalances (uncommon at recommended doses)
- Adrenal suppression with prolonged use
Why Veterinarians Choose Predef 2X
✓ Proven Clinical Efficacy
Over 3 decades of successful use in veterinary practice with documented efficacy in peer-reviewed studies and clinical trials.
✓ Rapid Onset of Action
Noticeable improvement in inflammation and clinical symptoms typically observed within 30-60 minutes of administration.
✓ Versatile Multi-Species Application
Single product covers treatment needs across horses, cattle, and swine, simplifying inventory management.
✓ Excellent Safety Profile
When used according to veterinary guidelines, Predef 2X demonstrates excellent tolerability across all target species.
✓ Cost-Effective Treatment
100mL multi-dose vial provides 5-50 treatments depending on species and condition, offering excellent value per treatment.
✓ Professional Grade Quality
Manufactured to pharmaceutical standards with comprehensive quality control ensuring consistent potency and sterility.
Comprehensive FAQ Section
Q: What conditions does Predef 2X injection treat in livestock?
A: Predef 2X treats inflammatory conditions including joint inflammation, allergic reactions, respiratory distress, ketosis in cattle, mastitis, retained placenta, muscle injuries in horses, and various stress-related conditions in swine.
Q: How quickly does Predef 2X work after injection?
A: Predef 2X is fast-acting with noticeable improvement typically seen within 30-60 minutes. Peak effects occur within 2-4 hours and duration of action is 12-24 hours depending on the condition and dose.
Q: Can I buy Predef 2X injection 100ml for multiple species?
A: Yes, Predef 2X is approved for use in horses, cattle, and swine. The same 100ml vial can be used across species with appropriate dosing adjustments for each animal type.
Q: What’s the difference between Predef 2X and other corticosteroid injections?
A: Predef 2X contains isoflupredone acetate, which is 4x more potent than prednisolone with faster onset, longer duration, and reduced side effects compared to older corticosteroids like dexamethasone.
Q: Is Predef 2X safe for pregnant animals?
A: Predef 2X should be used with caution in pregnant animals, especially during the first trimester. Always consult your veterinarian before treating pregnant livestock or breeding animals.
Q: How should I store Predef 2X injection after opening?
A: Store at room temperature (68-77°F), protect from light and freezing. Multi-dose vials maintain sterility for 28 days after first puncture when stored properly and accessed with sterile technique.
Q: What are the withdrawal periods for Predef 2X in food animals?
A: For cattle: 4 days for meat, 48 hours for milk. For swine: 5 days for meat. Always follow current FDA guidelines and consult your veterinarian for extended treatment protocols.
Q: Can Predef 2X be given intravenously to all species?
A: Yes, Predef 2X can be given IV or IM to horses and cattle. For swine, intramuscular injection is the preferred route. IV administration should be done slowly to prevent adverse reactions.
Q: How does Predef 2X help with ketosis in dairy cattle?
A: Predef 2X stimulates gluconeogenesis (glucose production), reduces ketone body formation, and improves appetite and feed intake, helping cows recover from ketosis more quickly than supportive care alone.
Q: Is Predef 2X effective for laminitis in horses?
A: Predef 2X can be used as part of laminitis management to reduce inflammation, but should only be used under strict veterinary supervision as corticosteroids can potentially worsen some cases of laminitis.
Q: Can Predef 2X be mixed with other injectable medications?
A: Do not mix Predef 2X with other medications in the same syringe unless specifically approved by the manufacturer. Administer separately to avoid drug interactions or incompatibilities.
Q: What should I do if an animal shows adverse reactions to Predef 2X?
A: Discontinue use immediately and contact your veterinarian. Provide supportive care as needed. Serious adverse reactions are rare but require prompt professional attention.
Q: How long can I use Predef 2X for chronic conditions?
A: Long-term use should be under strict veterinary supervision with regular monitoring. Generally, intermittent use is preferred over continuous therapy to minimize adverse effects.
Q: Does Predef 2X interfere with vaccines in livestock?
A: Avoid concurrent use with live virus vaccines as corticosteroids can suppress immune response. Wait at least 2 weeks after vaccination before using Predef 2X, or consult your veterinarian for specific protocols.
Professional Ordering Information
Available Package Options:
- Single Vial: 100mL multi-dose (20-50 treatments depending on species)
- Case Pack: 12 x 100mL vials (professional volume pricing)
- Veterinary Practice Pack: 24 x 100mL vials (maximum savings for clinics)
Professional Features:
- DEA exempt – no special licensing required
- Veterinary legend drug – professional use only
- Lot tracking for inventory management
- Technical support available for dosing questions
- Professional literature available upon request
Shipping and Handling:
- Temperature-controlled shipping available
- 2-3 day delivery with tracking
- Professional packaging with handling instructions
- Veterinary wholesaler pricing available
- Free shipping on qualifying orders
Quality Guarantee:
- 100% satisfaction guarantee
- Full potency guaranteed until expiration
- Sterility assurance with proper handling
- Professional support for any questions
- Return policy for unused products
Ready to provide your animals with professional-grade anti-inflammatory care? Order Predef 2X Injection 100ml today and ensure rapid, reliable treatment for inflammatory conditions across your horses, cattle, and swine.
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